Advanced Functional Materials·· 10 小时前精选AI 评分58
分区海绵通过选择性过滤与 Nb2C/CeO2 氧化还原干预实现止血和糖尿病创面再生
Bioinspired Compartmentalized Sponge Integrating Active Biological Filtration and Redox Intervention for Hemostasis and Diabetic Wound Regeneration
AI 导读
研究报道了一种分区海绵，在朝外无规孔层与贴组织取向孔层之间嵌入选择性膜，驱动血浆和微尺度病原体向外迁移，同时截留红细胞和血小板以加速界面凝血。基质中引入的 Nb2C/CeO2（NbCe）异质结能带结构与细菌呼吸链的生物氧化还原电位匹配，可自发产生界面电子外流并干扰微生物电子传递链。该海绵相比商用 Celox 将止血时间和失血量降低约 80%，第 15 天创面闭合率达 95.1%。
推荐理由
该海绵用选择性膜与定向孔道把渗出液外排与再生组分截留分开，并给出与 Celox 的止血对比数据。
创新点
把尺寸排阻式选择性过滤与能带匹配的界面电子转移结合在同一分区结构中，用物理筛分和热力学 biocatalysis 同时处理渗出液清除与微生物灭活。
图表、补充材料与最终表述以原文为准。阅读原文
来源：Advanced Functional Materials · doi.org
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