Small·· 7 小时前AI 评分42
丝素离聚物生物杂化纳米壳集成荧光纳米金刚石，构建保护性且光学响应的β细胞界面
Silk Ionomer Biohybrid Nanoshells Integrating Fluorescent Nanodiamonds for Protective and Optically Responsive β‐Cell Interfaces
AI 导读
丝素离聚物经静电层层组装在胰腺β细胞球体上形成超薄共形包覆，并掺入含氮-空位（NV）中心的羧基化荧光纳米金刚石。该涂层保持球体代谢活性与葡萄糖响应性胰岛素分泌，纳米金刚石呈pH响应光学行为，经荧光寿命成像定位于包覆球体界面并与丝素基质区分。瞬态丝素纳米壳可提供早期细胞保护并减少长期传输限制，定量传感仍需NV弛豫测量或光探测磁共振等自旋相关测量。
图表、补充材料与最终表述以原文为准。阅读原文
来源：Small · doi.org
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