Advanced Functional Materials·· 5 小时前精选AI 评分58
仿生螺旋水凝胶支架以Janus润湿性实现磁热双响应三尖瓣修复
Bioinspired Helical Hydrogel Scaffold with Janus Wettability for Magnetically and Thermally Responsive Tricuspid Valve Repair
AI 导读
研究团队提出一种仿生螺旋水凝胶支架，采用三层水凝胶体系与Janus润湿性界面，用于磁响应与热响应三尖瓣修复。支架一面为疏水PDMS/CNT/Fe3O4表面以抗血栓，另一面为亲水P(HEMA-co-AAm)表面以增强组织粘附；Fe3O4纳米颗粒赋予磁响应，可在外部磁场下远程非接触夹持，温敏P(NiPAAm-bis-AA)水凝胶则在生理温度下提供原位机械锚定与动态粘附。
推荐理由
该支架把磁响应夹持与温敏锚定集成到三层水凝胶中，并给出体外、离体猪心与体内评价，可供做心脏介入水凝胶器件的人参考结构设计。
创新点
将磁响应非接触夹持与温敏原位锚定集成在同一螺旋三层水凝胶支架中，并用Janus润湿性把抗血栓面与组织粘附面分开，形成无需缝合的经导管固定方案。
图表、补充材料与最终表述以原文为准。阅读原文
来源：Advanced Functional Materials · doi.org
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