ACS Nano·· 11 小时前AI 评分38
时序给药调控肝-血-肿瘤轴谷胱甘肽梯度，提升前药纳米组装体化疗效力
Temporal Dosing Tunes Glutathione Gradient across Liver-Blood-Tumor Axes to Boost the Chemotherapeutic Potency of Prodrug Nanoassemblies
AI 导读
将含α-二硫键、乙二醇片段与短碳链的三合一释药模块共价接枝到紫杉醇（PTX）上，构建出PSBA10、PSBA12、PSBA14三种前药纳米组装体，其中碳链最短的PSBA10 NPs表现出超灵敏氧化还原响应释药。
图表、补充材料与最终表述以原文为准。阅读原文
来源：ACS Nano · doi.org
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