Advanced Science·· 7 小时前精选AI 评分62
可编程编织丝-玻纤复合韧带在兔 ACL 重建中 4 周恢复跳跃功能
A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery
AI 导读
研究团队用可规模化的三维编织工艺制备了丝-玻纤（SF-GF）复合韧带，通过调节编织角度获得可编程的非线性力学与粘弹性，复现天然韧带的应变硬化响应和抗蠕变性能。富丝区域促进骨韧带整合与成骨分化，玻纤提供高强度并为仿生矿化提供基础；有限元模拟解释了载荷由丝向玻纤的应变依赖传递。在兔 ACL 重建中，角度优化的 SF-GF 在 4 周内促进腱-骨愈合并恢复功能性跳跃能力。
推荐理由
通过编织角度调控丝-玻纤复合韧带的非线性力学，并在兔 ACL 重建中 4 周恢复跳跃功能，展示了结构可设计的软硬组织修复路线。
创新点
以编织角度作为单一调控参数，在同一材料体系中同时实现天然韧带的 J 形应力-应变曲线与抗蠕变，并用有限元说明丝与玻纤之间的应变依赖载荷传递。
图表、补充材料与最终表述以原文为准。阅读原文
来源：Advanced Science · doi.org
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