Advanced Functional Materials·· 6 小时前AI 评分46
内吞型 pH 敏感 EGCG–赖氨酸纳米粒调控线粒体生物能量与钙信号以增强 NSC 介导的阿尔茨海默病治疗
Endocytosed pH‐Sensitive Nanoparticles Orchestrate Mitochondrial Bioenergetics and Calcium Signaling to Boost NSC‐Mediated Alzheimer's Therapy
AI 导读
溶酶体响应型 EGCG–赖氨酸纳米粒（EL NPs）在内吞-溶酶体解体后释放活性组分，清除 ROS 并经 AMPK 信号恢复线粒体生物能量，激活 Ca²⁺ 依赖 MAPK 通路促使 NSC 向 GABA 能神经元谱系分化。
图表、补充材料与最终表述以原文为准。阅读原文
来源：Advanced Functional Materials · doi.org
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